Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose

✍ Scribed by Obach, R. Scott; Kalgutkar, Amit S.; Soglia, John R.; Zhao, Sabrina X.

• Book ID: 125509197
• Publisher: American Chemical Society
• Year: 2008
• Tongue: English
• Weight: 403 KB
• Volume: 21
• Category: Article
• ISSN: 0893-228X
• DOI: 10.1021/tx800161s