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Can IL-6 blockade rectify imbalance between Tregs and Th17 cells?

✍ Scribed by Tanaka, Toshio


Book ID
120526595
Publisher
Future Medicine
Year
2013
Tongue
English
Weight
579 KB
Volume
5
Category
Article
ISSN
1750-743X

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## Abstract Regulatory T (T~reg~) cells play a key role in the maintenance of the immune system homeostasis. T~reg~ cells can be generated in the periphery under control of TGF‐β, a cytokine involved in the negative control of the immune system. However, TGF‐β cooperates with IL‐6 in the generation