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Can desensitization of the B-cell to D-glucose be simulated in cultured pancreatic islets?

✍ Scribed by Malaisse-Lagae, Francine ;Sener, Abdullah ;Malaisse, Willy J.


Book ID
110656317
Publisher
Springer-Verlag
Year
1987
Weight
528 KB
Volume
24
Category
Article
ISSN
0001-5563

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## Abstract Tumoral pancreatic islet cells of the RIN5mF line were incubated for 120 min in media prepared in ^2^H~2~O and containing D‐[1‐^13^C]glucose, and D‐[2‐^13^C]glucose, and D‐[6‐^13^C]glucose. The generation of C~2~‐ and C~3~‐ deuterated lactic acid was assessed by ^13^C NMR. The interpret