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Camptothecin-mediated apoptosis and antiproliferation effect is accompanied by down-regulation of telomerase activity in HaCaT cells

✍ Scribed by Liu, Xiaoming; Lin, Jingrong; Bao, Yongming; Lin, Xiran; An, Lijia


Book ID
119293151
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
181 KB
Volume
42
Category
Article
ISSN
0923-1811

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## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the