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Camptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53

✍ Scribed by Cheng, F; Liu, J; Teh, C; Chong, S-W; Korzh, V; Jiang, Y-J; Deng, L-W

Book ID
109972920
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
804 KB
Volume
30
Category
Article
ISSN
0950-9232

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## Abstract RBM5 (RNA‐binding motif protein 5) is a nuclear RNA binding protein containing 2 RNA recognition motifs. The __RBM5__ gene is located at the tumor suppressor locus 3p21.3. Deletion of this locus is the most frequent genetic alteration in lung cancer, but is also found in other human can