## Abstract The objective of this multicenter crossโsectional study was to determine the prevalence of fatigue and factors contributing to it in a large sample of Japanese patients with Parkinson's disease (PD). We used the 16โitem Parkinson Fatigue Scale (PFSโ16), which was designed to assess fati
Camptocormia in Japanese patients with Parkinson's disease: A multicenter study
โ Scribed by Morinobu Seki; Kazushi Takahashi; Atsuo Koto; Ban Mihara; Yoko Morita; Kazuo Isozumi; Kouichi Ohta; Kazuhiro Muramatsu; Jun Gotoh; Keiji Yamaguchi; Yutaka Tomita; Hideki Sato; Yoshihiro Nihei; Satoko Iwasawa; Norihiro Suzuki; on behalf of Keio Parkinson's Disease Database
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 264 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Objective:
The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients.
Background:
Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size.
Methods:
We evaluated 531 PD patients (disease duration: 7.0 ยฑ 5.5 years, mean ยฑ standard deviation). We examined their clinical features and the prevalence of camptocormia.
Results:
Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (Lโdopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05).
Conclusions:
Camptocormia is uncommon in PD and is associated with disease severity, higher Lโdopa dose and higher frequencies of autonomic symptoms. ยฉ 2011 Movement Disorder Society
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