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cAMP-dependent phosphorylation of the cardiac L-type Ca channel: A missing link?

✍ Scribed by P. Charnet; P. Lory; E. Bourinet; T. Collin; J. Nargeot


Book ID
116121806
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
399 KB
Volume
77
Category
Article
ISSN
0300-9084

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Voltage-dependent regulation of L-type c
✍ FranΓ§ois Tiaho; JoΓ«l Nargeot; Sylvain Richard πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 753 KB

The beta-adrenergic cascade is important for the regulation of voltage-dependent Ca channels by phosphorylation. Here we report that isoproterenol (ISO) profoundly alters the voltage-dependent properties of L-type Ca channels studied in rat ventricular cells. ISO (1 microM) shifted both threshold an