Camouflage and sabotage: tumor escape from the immune system
β Scribed by Isabel Poschke; Dimitrios Mougiakakos; Rolf Kiessling
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 384 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0340-7004
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It is often assumed that tumor rejection is mainly the result of cytotoxic T lymphocytes (CTLs) killing the tumor cells. However, recent studies have demonstrated that the rejection process is not as simple as this. In some models, tumors are rejected in the absence of lytic mechanisms (e.g. perfori