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Calyculin A and okadaic acid: Inhibitors of protein phosphatase activity

✍ Scribed by H. Ishihara; B.L. Martin; D.L. Brautigan; H. Karaki; H. Ozaki; Y. Kato; N. Fusetani; S. Watabe; K. Hashimoto; D. Uemura; D.J. Hartshorne

Book ID
115762206
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
452 KB
Volume
159
Category
Article
ISSN
0006-291X

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We have reported that treatment with okadaic acid, a potent protein phosphatase inhibitor, has the ability to enhance the synthesis of the 78-kDa glucose-regulated protein (GRP78). This article reports our investigation of another protein phosphatase inhibitor, calyculin A, demonstrating the signali