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Calpastatin reduces methamphetamine-induced induction in c-Jun phosphorylation, Bax and cell death in neuroblastoma SH-SY5Y cells

✍ Scribed by Jirapa Chetsawang; Wilasinee Suwanjang; Nipawan Pirompul; Piyarat Govitrapong; Banthit Chetsawang


Book ID
116773677
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
530 KB
Volume
506
Category
Article
ISSN
0304-3940

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## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein