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Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis

✍ Scribed by Vivek Kohli*; John F. Madden‡; Rex C. Bentley‡; Pierre-Alain Clavien*

Book ID
118521839
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
741 KB
Volume
116
Category
Article
ISSN
0016-5085

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✍ Surinder S. Yadav; David N. Howell; Douglas A. Steeber; Robert C. Harland; Thoma 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 738 KB

Hepatic damage following ischemia-reperfusion injury involves polymorphonuclear leukocytes (PMN) and platelet sequestration, however the mechanisms of adhesion remain elusive. In this study, using gene-targeted deficient mice, we evaluated P-selectin and its contribution to PMN and platelet adhesion