New inhibitors of calpain prevent degrad
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T. James; D. Matzelle; R. Bartus; E.L. Hogan; N.L. Banik
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Article
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1998
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John Wiley and Sons
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English
โ 66 KB
๐ 1 views
We have determined the effects of the calpain inhibitors AK275 and AK295 upon purified m-calpain and calcium-mediated degradation of neurofilament protein (NFP) in rat spinal cord in vitro. After incubation, the soluble radioactivity and/or extent of myelin basic protein (MBP) or NFP degradation was