N-terminal cleavage of Bax by calpain ge
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Gui Gao; Q. Ping Dou
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Article
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2000
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John Wiley and Sons
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English
โ 367 KB
Upon apoptosis induction, the proapoptotic protein Bax is translocated from the cytosol to mitochondria, where it promotes release of cytochrome c, a caspase-activating protein. However, the molecular mechanisms by which Bax triggers cytochrome c release are unknown. Here we report that before the i