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Calpain 1-protein kinase C complex: effect of calpain inhibitors after dissociation

✍ Scribed by SAVART, M; PALLET, V; LETRAD, P; BOSSUET, C; DUCASTAING, A

Book ID
122600632
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
872 KB
Volume
73
Category
Article
ISSN
0300-9084

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## Abstract Using a calpain/protein kinase C (PKC) complex, we were able to reproduce, __in vitro__, the induction of PKC down‐regulation by the phorbol ester 12‐O‐tetradecanoyl‐phorbol‐13‐acetate (TPA) which had been previously observed in cells. We show that TPA initiates this phenomenon by promo