Purified L-asparaginase of Tetrahymena pyriformis is a multi-subunit enzyme exhibiting protein kinase activity as well. The enzyme's L-asparaginase activity is affected by its phosphorylation state. Both native and dephosphorylated L-asparaginase show antiproliferative activity on three breast cance
Calmodulin modulates Akt activity in human breast cancer cell lines
β Scribed by Christine M. Coticchia; Chetana M. Revankar; Tushar B. Deb; Robert B. Dickson; Michael D. Johnson
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 713 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0167-6806
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MATERIAL AND METHODS ## Cell culture Out of 10 human breast-carcinoma cell lines studied, 6 were derived from metastatic carcinoma as follows: MCF7, T47D, ZR 75-1, SKBR3