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Calmodulin kinase II activation of mitogen-activated protein kinase in PC12 cell following all-trans retinoic acid treatment

✍ Scribed by Jiangong Liu; Ran Zhou; Quanren He; Wan-I. Li; Ting Zhang; Bo Niu; Xiaoying Zheng; Jun Xie

Book ID
116780055
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
358 KB
Volume
30
Category
Article
ISSN
0161-813X

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## Abstract All‐trans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (