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Calmodulin- and protein phosphorylation-independent release of catecholamines from PC-12 cells

✍ Scribed by Heinrich J.G. Matthies; H.Clive Palfrey; Richard J. Miller


Book ID
115921185
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
516 KB
Volume
229
Category
Article
ISSN
0014-5793

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PC12 cells are a nerve growth factor-responsive clone derived from a rat pheochromocytoma. The cells contain catecholamines and secrete them in response to depolarizing stimuli and cholinergic agonists. Treatment of the cells with nerve growth factor produces a number of very rapid changes, includin