๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Call for abstracts Fifth International Conference on Emergency Medicine


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
104 KB
Volume
22
Category
Article
ISSN
1097-6760

No coin nor oath required. For personal study only.

โœฆ Synopsis


the maximum milk concentration was 7.9 ng/mL and the maximum milkto-plasma ratio was 0.025. Caution should be exercised when TORADOUM or R~&& is administered to a nursing woman.

Pediatric Use

Safety and efficacy in children have not been established. Therefore, TORADOL is not recommended for use in children.

Use in the Elderly

Because ketoro]ac tramethamine is cleared somewhat more slowly by the elderly (sea CLINICAL PHARMACOLOGY section of full prescribing information) who are atso more sensitive to the renal effects of NSAtDs (see PRECAUTIONS --Renal Effects), extra caution and reduced dosages (see DOSAGE AND ADMINISTRATION section of full prescribing information) should be used when treating the elderly with TORADOL.

ADVERSE REACTIONS

Adverse reaction rates from short-term use of NSAIDs are generally from 1/10 to 1/2 the rates associated with long-term use. This is also true for TORADOL. Adverse reaction rates also may increase with higher doses of TORADOL (see WARNINGS, and DOSAGE AND ADMINISTRATION section o1 full prescribing information). TORADOU-M is indicated for short-term use. Physicians using TORADOL -M should be alert for the usual complications of NSAID treatment, and should be aware that with longer use (exceeding 5 days) of TORADOU M, the frequency and severity of adverse reactions may increase. Physicians using TORADOLO~aL should be alert to the relative risks associated with dose and dose duration as described in CLINICAL PHARMACOLOGY --Clinical Studies section of full prescribing information. Physicians using TORADOL should be alert for the usual complications o1 NSAID treatment. The adverse reactions listed below were reported in clinical trials with TORADOL in which patients received up to 20 doses, in 5 days, of TORADOU v 30 mg or up to 4 doses a day from long-term studies of TORADOL oRAL 10 mg OlD. In addition, adverse reactions that were reported from TORADOL~. post-marketing surveillance, are included in "Incidence 1% or Less." Incidence Greater than 1% (probably causally related


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