Calixarene amino acids; building blocks for calixarene peptides and peptide-dendrimers

✍ Scribed by Heng Xu; Gary R Kinsel; Jiang Zhang; Meiling Li; Dmitry M Rudkevich

• Book ID: 104205559
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 682 KB
• Volume: 59
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(03)00947-5

✦ Synopsis

A modular strategy towards receptor macromolecules is presented, which combines synthetically diverse peptide synthesis with highly functional calixarene chemistry. The design and synthesis of calix[4]arene amino acids 1a -f, calix-lysines, is described, which were used as construction blocks to assemble nanoscale, multivalent entities-calix -peptides 2 and calix -peptide-dendrimers 3.