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Calix[4]arene phosphonates - recognition of amino alcohols in water

✍ Scribed by Dariusz Witt; Joanna Dziemidowicz; Janusz Rachon


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
127 KB
Volume
15
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

The water‐soluble calix[4]arenes based cavitands were obtained in good yield by introduction of phosphonic acids groups at the upper rim; we describe the design, synthesis, and formation of the complexes with ephedrine, norephedrine, and noradrenaline hydrochloride in the phosphate buffer at pD 7.3. Β© 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:155–161, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10229


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## Abstract The __p‐tetra__‐te__r__t‐butyl calix[4] arene derivatives (3 and 4) with (5,5) chiral bicyclic guanidinium, as the receptors of amino acid zwitterions, have been synthesized __via__ a O‐alkylation reaction of __p‐tetra__‐tert‐butyl calix [4] arene with cbJoromethyl chiral bicyclic guani