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Calcium/calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic β-cells

✍ Scribed by Yasunori Sugiyama; Koji Murao; Hitomi Imachi; Noriyuki Sueyoshi; Toshihiko Ishida; Isamu Kameshita


Book ID
113799106
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
522 KB
Volume
60
Category
Article
ISSN
1532-8600

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Recent studies suggest that CaM kinase II is involved in light-induced phase delays and induction of Per1 and Per2 genes in the hamster suprachiasmatic nucleus (SCN) (Yokota et al.,2001). We focused on intracellular mechanisms of the CaM kinase II-induced mPer1 gene expression. Immunoblotting and im