✦ LIBER ✦
Calcium regulation of phosphatidyl inositol turnover in macrophage activation by formyl peptides
✍ Scribed by Andrij Holian; Douglas F. Stickle
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 758 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
mechanism which couples the specific receptor binding w i t h the cellular response, and the roles and sequence of these observed intracellular phenomena, have not been clearly delineated. One hypothesis being tested in a number of different cells i s that upon recognition of a stimulus, a phospholipase C i s activated which cleaves the inositol phosphate(s) portion from phosphatidyl inositols yielding diacylglycerol, which i s reported to activate protein kinase C (Kishimoto et al., 19801, and inositol phosphates, which have been shown to effec-