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Calcium regulates the PI3K-Akt pathway in stretched osteoblasts

✍ Scribed by Theodora E Danciu; Rosalyn M Adam; Keiji Naruse; Michael R Freeman; Peter V Hauschka


Book ID
117105106
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
200 KB
Volume
536
Category
Article
ISSN
0014-5793

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## Abstract Skeletal muscle cells are hypertrophied by mechanical stresses, but the underlying molecular mechanisms are not fully understood. Two signaling pathways, phosphatidylinositol 3‐kinase (PI3K)/Akt to target of rapamycin (TOR) and extracellular signal–regulated kinase kinase (MEK) to extra