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Calcium Phosphate Crystallization on Electrospun Cellulose Non-Woven Fabrics Containing Synthetic Phosphorylated Polypeptides

✍ Scribed by Shinya Hayashi; Kousaku Ohkawa; Hiroyuki Yamamoto; Mina Yamaguchi; Shigenari Kimoto; Shigeaki Kurata; Hisaaki Shinji


Book ID
102939832
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
566 KB
Volume
294
Category
Article
ISSN
1438-7492

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✦ Synopsis


Abstract

The preparation of electrospun non‐woven fabrics composed of cellulose and synthetic phosphorylated polypeptides, copoly[Ser(PO~3~H~2~)^X^Asp^Y^]s (X:Y = 100:0, 75:25, 50:50, 25:75), is described. The non‐wovens were subjected to an alternate immersion in CaCl~2~ and Na~2~HPO~4~ solutions to induce crystallization of calcium phosphate. The deposited calcium phosphate crystals were analyzed by means of EDX analysis and WXRD. The amounts of calcium phosphate deposition are greater for the cellulose non‐woven fabrics containing copoly[Ser(PO~3~H~2~)^X^Asp^Y^] than those of cellulose‐only non‐woven fabrics. These results indicate that copoly[Ser(PO~3~H~2~)^X^Asp^Y^] can entrap Ca^2+^ ions around the fine fiber matrix to accelerate crystallization of the calcium phosphate.

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