Calcium oxalate nephrolithiasis and expression of matrix GLA protein in the kidneys
โ Scribed by Aslam Khan, Wei Wang, Saeed R. Khan
- Book ID
- 120784201
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 853 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0724-4983
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๐ SIMILAR VOLUMES
Matrix Gla protein (MGP), is a vitamin-K-dependent protein which is synthesized in a variety of tissues such as lung, heart, kidney, cartilage and bone. The function of MGP in these tissues is unclear. We have previously reported elevated MGP mRNA levels in a breast-cancer cell line, 600PE1, as comp
The present studies demonstrate that the expression of the vitamin K-dependent matrix Gla protein (MGP) is critically dependent on cell density in culture. Subculture of confluent NRK cells to 1/30 of the confluent cell density causes a 50-to 100-fold decline in MGP expression per cell within two da