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Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells

✍ Scribed by Z.-M. Liu; G. G. Chen; A. C. Vlantis; G. M. Tse; C. K. Y. Shum; C. A. van Hasselt

Book ID
105758625
Publisher
Springer
Year
2007
Tongue
English
Weight
633 KB
Volume
64
Category
Article
ISSN
1420-682X

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## Abstract Numerous studies have documented that Sp1 expression level were elevated in various human cancers. However, the promoters of many pro‐apoptotic genes have been found to contain the Sp1 binding elements and are activated by Sp1 overexpression. To better understand the role and the mechan