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Calcium leak through ryanodine receptor is involved in neuronal death induced by mutant huntingtin

✍ Scribed by Mari Suzuki; Yoshitaka Nagai; Keiji Wada; Tatsuro Koike


Book ID
119194758
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
721 KB
Volume
429
Category
Article
ISSN
0006-291X

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## Abstract Disturbances in neuronal calcium homeostasis have been implicated in a variety of neuropathological conditions, including cerebral ischemia, hypoglycemia, and epilepsy, and possibly constitute part of the cell death process associated with chronic neurodegenerative disorders. We investi