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Calcium ionophore plus excision induce a large conductance chloride channel in membrane patches of human colon carcinoma cells HT-29cl.19A

โœ Scribed by R. B. Bajnath; J. A. Groot; H. R. de Jonge; M. Kansen; J. Bijman


Publisher
Springer
Year
1993
Tongue
English
Weight
371 KB
Volume
49
Category
Article
ISSN
1420-682X

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The human colonic carcinoma cell line HT-29cl.19A responds to the protein kinase C activator PDB (4-beta-phorbol 12,13-dibutyrate), as it does to forskolin (an activator of adenylyl cyclase), with a secretory response when the cells are grown on filters and studied at 36 degrees C. Previously, we sh