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Calcium ionophore A 23187 induces arachidonic acid release from phosphatidylcholine in cultured human endothelial cells

✍ Scribed by J.M.F. Thomas; H. Chap; L. Douste-Blazy


Book ID
118315478
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
351 KB
Volume
103
Category
Article
ISSN
0006-291X

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Release of arachidonic acid from vascula
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Vascular endothelial cells respond to a variety of physiological and pharrnacological stimuli by releasing free arachidonic acid from membrane phospholipids, thus initiating synthesis of prostacyclin. Previous work in our laboratory has demonstrated that the thrombin-stimulated deacylation is specif