<p>The crucial role played by calcium as a cellular messenger has become increasingly evident, as has the recognition that cells spend much energy in maintaining the cytosolic concentration of this cation both constant and low. It is thought they do this to avoid precipitating phosphate, needed as a
Calcium Homeostasis
โ Scribed by Robert J. P. Williams (auth.), Professor Dr. Ernesto Carafoli, Priv.-Doz. Dr. Joachim Krebs (eds.)
- Publisher
- Springer-Verlag Berlin Heidelberg
- Year
- 2000
- Tongue
- English
- Leaves
- 191
- Series
- Topics in Biological Inorganic Chemistry 3
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
Volume III of this series deals with cellular calcium homeostasis aspects and structural properties of extra- and intracellular calcium-binding proteins are described. The structure/function relationship of calcium-transport proteins, and the role of calcium as a regulator of the activity specific protein kinases and phosphatase(s) are also described. The volume is a valuable source of information for graduate students and researchers who want to acquaint themselves with various aspects extracellular calcium. .
โฆ Table of Contents
Front Matter....Pages I-IX
Calcium Homeostasis and Its Evolution....Pages 1-28
Evolution of EF-Hand Proteins....Pages 29-58
Calmodulin Target Recognition: Common Mechanism and Structural Diversity....Pages 59-81
Calcium-Binding EGF-like Domains....Pages 83-99
Calmodulin-Dependent Protein Kinases....Pages 101-123
Structure of Calcineurin and Its Complex with Immunophilins....Pages 125-141
The Ca 2+ Pump of Sarcoplasmic and Endoplasmic Reticulum Membranes....Pages 143-154
The Plasma Membrane Ca 2+ ATPase....Pages 155-171
The Na + /Ca 2+ Exchanger: Structural Aspects, Function and Regulation....Pages 173-188
โฆ Subjects
Biochemistry, general; Pharmacology/Toxicology; Molecular Medicine; Human Physiology; Inorganic Chemistry
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