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Calcium enhances the proteolytic activity of BACE1: An in vitro biophysical and biochemical characterization of the BACE1–calcium interaction

✍ Scribed by Michael Hayley; Samantha Perspicace; Therese Schulthess; Joachim Seelig


Book ID
116274836
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
396 KB
Volume
1788
Category
Article
ISSN
0005-2736

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## Abstract Mammalian acrosome reaction (AR) requires successive activation of three different types of calcium channels (T‐type channels, Inositol‐3‐phosphate (InsP3) receptors, and TRPC2 channels). All the calcium signaling is under the control of the activation of the first‐one, a T‐type calcium