Calcium effects on gap junction structure and cell coupling
β Scribed by PERACCHIA, CAMILLO
- Book ID
- 109708626
- Publisher
- Nature Publishing Group
- Year
- 1978
- Tongue
- English
- Weight
- 863 KB
- Volume
- 271
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/271669a0
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## Abstract Gap junction communication is widespread throughout the mammalian nervous system among neurons as well as glia. We addressed the hypothesis that general anesthetics attenuate gap junction mediated coupling in P19 cell line that can differentiate into neuronalβlike cells and astrocytes a
A general model for the transfer of ions and molecules between two cells via a gap junction is presented. This constitutes a dynamical system consisting of two connected parts: the dynamics of intracellular concentrations and electrical potentials, and the dynamics of the gating in the gap junction.