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Calcium-dependent effects of palmitate on β-cell apoptosis and function

✍ Scribed by James, Djohnson; Gwiazda, Kamila; Jeffrey, Kristin; Luciani, Dans

Book ID
121888200
Publisher
Canadian Diabetes Association
Year
2008
Tongue
English
Weight
543 KB
Volume
32
Category
Article
ISSN
1499-2671

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## Abstract Chronic exposure to elevated concentration of free fatty acids (FFA) has been verified to induce endoplasmic reticulum (ER) stress, which leads to pancreatic β‐cell apoptosis. As one of the medium and long chain FFA receptors, GPR40 is highly expressed in pancreatic β cells, mediates bo