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Calcium-Dependent Conformational Rearrangements and Protein Stability in Chicken Annexin A5

✍ Scribed by Turnay, Javier; Olmo, Nieves; Gasset, María; Iloro, Ibón; Arrondo, José Luis R.; Antonia Lizarbe, M.

Book ID
118514652
Publisher
Biophysical Society
Year
2002
Tongue
English
Weight
206 KB
Volume
83
Category
Article
ISSN
0006-3495

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Nereis sarcoplasmic Ca 2؉ -binding protein (NSCP) is a calcium buffer protein that binds Ca 2؉ ions with high affinity but is also able to bind Mg 2؉ ions with high positive cooperativity. We investigated the conformational and stability changes induced by the two metal ions. The thermal reversible