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Calcium-dependent activation of human neutrophils by a synthetic ionophore

โœ Scribed by Prescott Atkinson; Roger L. Berkow


Book ID
115762145
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
419 KB
Volume
163
Category
Article
ISSN
0006-291X

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The phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and the calcium ionophore, A23187, have similar effects on many different cells. For example, both show mitogenic and comitogenic activities for lymphocytes. It had been suggested that some of TPA's effects are due to its ab