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Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle

✍ Scribed by Kareen L. Kreutziger; Nicoletta Piroddi; Jonathan T. McMichael; Chiara Tesi; Corrado Poggesi; Michael Regnier


Book ID
116986205
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
966 KB
Volume
50
Category
Article
ISSN
0022-2828

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πŸ“œ SIMILAR VOLUMES


The kinetic cycle of cardiac troponin C:
✍ Andrea L. Hazard; Susy C. Kohout; Nicole L. Stricker; John A. Putkey; Joseph J. πŸ“‚ Article πŸ“… 1998 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 983 KB

## Abstract The goal of this study is to characterize the kinetic mechanism of Ca^2+^ activation and inactivation of cardiac troponin C (cTnC), the Ca^2+^ signaling protein which triggers heart muscle contraction. Previous studies have shown that IAANS covalently coupled to Cys84 of wild‐type cTnC