𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Calcium antagonists as antiatherosclerotic drugs

✍ Scribed by Dr. George B. Weiss


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
377 KB
Volume
6
Category
Article
ISSN
0272-4391

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


1H-Indole Derivatives as Calcium Antagon
✍ Laura Garuti; Giuseppe Giovanninetti; Sergio Bova; Alberto Chiarini πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 540 KB

Two short series of compounds with IH-indole skeleton, bearing hydantoin and piperazine nuclei respectively, were synthesized. Some compounds of these two series were tested for their calcium-antagonistic activity on K+-depolarized smooth muscle (rabbit auricolar artery and guineapig taenia caeci) a

Penta-substituted benzimidazoles as pote
✍ Marc Gerspacher; Eva Altmann; RenΓ© Beerli; Thomas Buhl; Ralf Endres; Rainer Gams πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 784 KB

A series of novel benzimidazole derivatives has been designed via a scaffold morphing approach based on known calcilytics chemotypes. Subsequent lead optimisation led to the discovery of penta-substituted benzimidazoles that exhibit attractive in vitro and in vivo calcium-sensing receptor (CaSR) inh