๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Calcium and neuronal plasticity

โœ Scribed by Nelson, Phillip G. ;Fields, R. Douglas

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
106 KB
Volume
25
Category
Article
ISSN
0022-3034

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โœฆ Synopsis

The great generality of calcium as a cell biologic regulator and its natural relationship to electrical activity in neurons has made it an obvious candidate for a mediator of plasticity in the nervous system. This volume presents various strands of research that seek to establish specific ways in which this mediation may occur. In addition to concise reviews, this special issues offers new observations and fresh ideas. Controversies are addressed by experimental evidence related to such unresolved issues as the Hebbian model of synaptic plasticity at the neuromuscular junction, models of dendritic spines as calcium compartments, and theories of how calcium fluxes regulate growth cone motility and immediate-early gene expression.

Spectacular advances in calcium imaging have made possible the visualization of calcium compartmentalization (and limits of such compartmentalization) at the level of single neuronal/dendritic spines (Jaffey, Fisher and Brown; and Con-

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