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Calcium accumulation in neurites and cell bodies of rat cerebellar granule cells in culture: effects on GABAAreceptor function

✍ Scribed by A. Cupello; A. Esposito; C. Marchetti; F. Pellistri; M. Robello

Publisher
Springer
Year
2005
Tongue
English
Weight
170 KB
Volume
28
Category
Article
ISSN
0939-4451

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✍ Carmen Vale; Amparo Alfonso; Cristina SuΓ±ol; Mercedes R. Vieytes; Luis M. Botana πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 800 KB

## Abstract A channel open on the membrane can be formed by palytoxin (PTX). Ten nanomolar PTX caused an irreversible increase in the cytosolic calcium concentration ([Ca^2+^]~c~), which was abolished in the absence of external calcium. The increase was eliminated by saxitoxin (STX) and nifedipine