Caffeine-induced calcium release from the endoplasmic reticulum of acinar cells of the submandibular salivary gland
β Scribed by O. V. Kopach; I. A. Kruglikov; N. V. Voitenko; N. V. Fedirko
- Publisher
- Springer US
- Year
- 2007
- Tongue
- English
- Weight
- 371 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0090-2977
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## Abstract ## Background Serotonin induces fluid secretion from __Calliphora__ salivary glands by the parallel activation of the InsP~3~/Ca^2+^ and cAMP signaling pathways. We investigated whether cAMP affects 5-HT-induced Ca^2+^ signaling and InsP~3~-induced Ca^2+^ release from the endoplasmic r
Acetylcholine (ACh) caused repetitive transient CI-currents activated by intracellular Caz+ in single rat submandibular grand acinar cells. As the concentration of ACh increased the amplitude and the frequency of the transient CI-currents increased. These responses occurred also in the absence of ex