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Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells

✍ Scribed by Mohamed M M Abdel-Latif; Henry J Windle; Basma S El Homasany; Kamal Sabra; Dermot Kelleher

Book ID: 110008921
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 254 KB
Volume: 146
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0706421

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## Abstract Nuclear factor‐κB (NF‐κB) plays a major role in host inflammatory responses and carcinogenesis and as such is an important drug target for adjuvant therapy. In this study, we examined the effect of caffeic acid phenethyl ester (CAPE), an NF‐κB inhibitor, on __Helicobacter pylori__ (__H.

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