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Caenorhabditis elegans homologues of the CLN3 gene,mutated in juvenile neuronal ceroid lipofuscinosis

✍ Scribed by Gert De Voer; Gert Jansen; Gert-Jan B. Van Ommen; Dorien J.M. Peters; Peter E.M. Taschner


Book ID
114464910
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
555 KB
Volume
5
Category
Article
ISSN
1090-3798

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The neuronal ceroid lipofuscinoses (NCLs) are a heterogeneous group of autosomal recessive neurodegenerative diseases comprising Batten and other related diseases plus numerous variants. They are characterized by progressive neuronal cell death. The CLN6 gene was recently identified, mutations in wh