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Cadmium and cisplatin damage erythropoietin-producing proximal renal tubular cells

โœ Scribed by Hyogo Horiguchi; Etsuko Oguma; Fujio Kayama

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
481 KB
Volume
80
Category
Article
ISSN
0340-5761

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โœ SHANKS, JONATHAN H.; HILL, CLAIRE M.; LAPPIN, TERENCE R. J.; MAXWELL, A. PETER ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 510 KB

Erythropoietin (EPO) is the main humoral stimulus of erythropoiesis. In adult mammals, the kidney releases EPO in response to hypoxic stress. Conflicting data have suggested either renal tubular or peritubular cell origins of EPO synthesis in viva Zn situ hybridization studies were performed to defi