✦ LIBER ✦
Cachectin/TNF kills or inhibits the differentiation of 3T3-L1 cells according to developmental stage
✍ Scribed by Masanobu Kawakami; Nobumasa Watanabe; Hiroko Ogawa; Arata Kato; Hiroyuki Sando; Nobuhiro Yamada; Toshio Murase; Fumimaro Takaku; Seiichi Shibata; Toshitsugu Oda
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 862 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
The effects of cachectin/tumor necrosis factor (TNF) on growth and differentiation of 3T3-Ll cells were examined. This fibroblastic cell line can be induced to differentiate into a mature cell type having the biochemical and morphological characteristics of normal adipocytes. At various stages of growth and differentiation, 3T3-LI cells were exposed to 2.5 x M (4.2 fg/ml to 420 n g h l = ca. 1.2 x