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Cacalol, a natural sesquiterpene, induces apoptosis in breast cancer cells by modulating Akt-SREBP-FAS signaling pathway

✍ Scribed by Wen Liu; Eiji Furuta; Kazutoshi Shindo; Misako Watabe; Fei Xing; Puspa R. Pandey; Hiroshi Okuda; Sudha K. Pai; Laura L. Murphy; Deliang Cao; Yin-Yuan Mo; Aya Kobayashi; Megumi Iiizumi; Koji Fukuda; Bo Xia; Kounosuke Watabe

Publisher: Springer US
Year: 2010
Tongue: English
Weight: 483 KB
Volume: 128
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-010-1076-8

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## Abstract Triterpenes found in plants display a multitude of biological activities, including anti‐tumor properties. The present study investigates the effect of 18β‐glycyrrhetinic acid (GRA) a pentacyclic triterpenoid of the β‐amyrin type, isolated from the root of Licorice (__Glycyrrhizza glabr