Ca2+ signaling differentiation during oocyte maturation

✍ Scribed by Khaled Machaca

• Book ID: 102313327
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 278 KB
• Volume: 213
• Category: Article
• ISSN: 0021-9541
• DOI: 10.1002/jcp.21194

✦ Synopsis

Abstract

Oocyte maturation is an essential cellular differentiation pathway that prepares the egg for activation at fertilization leading to the initiation of embryogenesis. An integral attribute of oocyte maturation is the remodeling of Ca^2+^ signaling pathways endowing the egg with the capacity to produce a specialized Ca^2+^ transient at fertilization that is necessary and sufficient for egg activation. Consequently, mechanistic elucidation of Ca^2+^ signaling differentiation during oocyte maturation is fundamental to our understanding of egg activation, and offers a glimpse into Ca^2+^ signaling regulation during the cell cycle. J. Cell. Physiol. 213: 331–340, 2007. © 2007 Wiley‐Liss, Inc.