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Ca2+ Sensitivity of L-Type Calcium Channel Inactivation Probed by Ca2+ Photouncaging--- Window onto Calmodulinopathies

✍ Scribed by Limpitikul, Worawan; Yue, David T.


Book ID
123261384
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
144 KB
Volume
106
Category
Article
ISSN
0006-3495

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Activity of cardiac L-type Ca2+channels
✍ Christoph Romanin; Jan -Olof Karlsson; Hansgeorg Schindler πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 337 KB

Ca(2+)-induced inactivation of L-type Ca2+ channels is proposed as an important negative feedback mechanism regulating Ca2+ entry. Here, for the first time, evidence for modification of heart L-type Ca2+ channel activity by cytoplasmic calcium is provided from excised inside-out membrane patches. Ba