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Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells

✍ Scribed by Missiaen, Ludwig; De Smedt, Humbert; Droogmans, Guy; Casteels, Rik

Book ID
109780879
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
369 KB
Volume
357
Category
Article
ISSN
0028-0836

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Ca2+ dependence of inositol 1,4,5-trisph
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We have studied arginine vasopressin (AVP)-, thapsigarginand inositol 1,4,5trisphosphate (InsPJ-mediated CaL+ release in renal epithelial LLC-PK, cells. AVP-induced changes in the intracellular free calcium concentration ([Ca"],) were studied in indo-1 loaded single cells by confocal laser cytometry