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Ca2+-mobilising properties of synthetic fluoro-analogues of myo-inositol 1,4,5-trisphosphate and their interaction with myo-inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase

โœ Scribed by Stephen T. Safrany; Deborah Sawyer; Richard J.H. Wojcikiewicz; Stefan R. Nahorski; Barry V.L. Potter


Book ID
115923333
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
474 KB
Volume
276
Category
Article
ISSN
0014-5793

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Synthesis of (ยฑ)-myo-inositol 1,4,5-tris
โœ Nicholas J. Noble; Allan M. Cooke; Barry V.L. Potter ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 758 KB

Novel routes to myo-inositol 1,4,5trisphosphate and a phosphorothioate analogue involving mixed P(V) and P(III) chemistry have been developed. Phosphorylation of 2,3,6-tri-O-benzyl-myo-inositol l-[di-(2,2,2-trichloroethyl) phosphate] with bis(2,2,2-trichloroethyl) phosphorochloridate gave a mixture