Activity-dependent somatostatin gene exp
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Isabel Sรกnchez-Muรฑoz; Franco Sรกnchez-Franco; Mario Vallejo; Antonio Fernรกndez; N
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Article
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2009
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John Wiley and Sons
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English
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## Abstract Ca^2+^ influx through Lโtype voltageโgated Ca^2+^ channels (LโVSCC) is required for K^+^โinduced somatostatin (SS) mRNA. Increase in intracellular Ca^2+^ concentration leads to the activation of cyclic AMPโresponsive element binding protein (CREB), a key regulator of SS gene transcripti